The purpose of this experiment is to synthesis triphenylmethanol by using Grignard reagent. In order to synthesis triphenylmethanol, Grignard reagent is playing an important role because Grignard reagent is the key reagent in this experiment. The presence of water in the process of generating Grignard reagent will causes the particular reagent to be decomposed.
Reactions of alcohols Video transcript In this video we'll see how to synthesize alcohols using the Grignard reagents.
So first, we have to learn how to make a Grignard reagent. So you start with an alkyl halide, so over here on the left. And you add a magnesium metal. And you need to add something like diethyl ether as your solvent.
You can't have any water present because water will react with the Grignard reagent. And so this is what you make, over here on the right. You end up with a carbon atom bonded to a metal.
So carbon is bonded to magnesium. This is called an organometallic bond.
And you can do this with other metals. You can do this with lithium, for example. But Grignard reagents are one of those things that's always talked about in undergraduate organic chemistry classes.
And you can see that these two electrons here, these red ones, the ones in red. I've drawn it like a covalent bond.
The bond between carbon and magnesium. But in reality, it's more ionic than covalent.
So it's equivalent to the second structure down here. Now, in terms of electronegativities, carbon is actually more electronegative than magnesium. So the two electrons in red are actually going to be closer to the carbon atom, itself, giving the carbon a negative charge, and forming a carbanion.
And so this is a carbanion that is formed.
And this is unique because this carbanion can now act as a nucleophile in your mechanism to make alcohols.Experiment 3: The Grignard Reaction Background: The haloalkanes, also known as alkyl halides, R-X, are a group of chemical compounds comprised of an Grignard 3 I.
Triphenylmethanol Preparation Summary: First the Grignard reagent, phenyl magnesium bromide, will be prepared by reacting Mg with injecting the ether via syringe needle.
The synthesis of a Grignard reagent was required for the Grignard reaction of this experiment to occur, therefore, phenylmagnesium bromide was produced before further proceeding with the preparation of triphenylmethanol.
The Grignard Reaction – Synthesis of Triphenylmethanol Andrea Mxxxxxxx Section Experiment 10 MM/DD/ Grignard reagents form via the reaction of an alkyl or aryl halide with magnesium metal.
The reaction is conducted by adding the organic halide to a suspension of magnesium in an etherial solvent, which provides ligands required to stabilize the organomagnesium compound.
The Grignard Reaction – Synthesis of Triphenylmethanol Andrea Mxxxxxxx Section Experiment 10 MM/DD/ Synthesis of Alcohols via Grignard Reactions Conclusion In this lab, we saw the utility of Grignard reactions in synthesizing alcohols, as we were finally able to synthesize triphenyl methanol from the given carbonyl compound, methyl benzoate, by using Grignard synthesis with bromobenzene%(6).